Kornblum Oxidation Meaning. The burning of fuels, the corrosion of metals, and even the processes of photosynthesis and cellular respiration involve oxidation. A highly efficient molecular iodine mediated formal [3 + 2 + 1] cycloaddition reaction enables the direct synthesis of substituted quinolines from methyl ketones, arylamines, and.


Kornblum Oxidation Meaning

(1959) a primary tosylate is heated at 150 o to cause s n 2 displacement by the oxygen of dimethyl sulfoxide (dmso) in the presence of nahco 3. In kornblum oxidation, the reaction uses iodine and dimethylsulfoxide and proceeds through the formation of arylglyoxal as the key intermediate.

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